Article
Impact of <i>Helicobacter pylori</i> Virulence Factors and Compounds on Activation and Maturation of Human Dendritic Cells
22 Jun 2005
Abstract excerpt
Recently, we and others have shown that Helicobacter pylori induces dendritic cell (DC) activation and maturation. However, the impact of virulence factors on the interplay between DCs and H. pylori remains elusive. Therefore, we investigated the contribution of cag pathogenicity island (PAI) and VacA status on cytokine release and up-regulation of costimulatory molecules in H. pylori-treated DCs. In addition, to...
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