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Article

Novel mutations in testis-specific ubiquitin protease 26 gene may cause male infertility and hypogonadism.

Reproductive biomedicine online - 1 Jun 2005

Paduch Darius A, Mielnik Anna, Schlegel Peter N

Abstract excerpt

Patients (n = 188) with non-obstructive azoospermia (NOA), and 17 fertile controls were screened for sequence changes in the ubiquitin specific protease (USP) 26 gene. Semen analysis, hormonal evaluation, and testicular biopsies were performed. DNA was extracted from whole blood. Denaturing high-performance liquid chromatography was used to screen for single nucleotide polymorphisms. Amino acid sequences were...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15970005
DOI: 10.1016/s1472-6483(10)61119-4

Genes

USP26

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel mutations in testis-specific ubiquitin protease 26 gene may cause male infertility and hypogonadism.PMID 15970005Read ↗

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