Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Mutations in X-Linked, USP26-Induced Asthenoteratozoospermia and Male Infertility.

Cells - 25 Jun 2021

Liu Chunyu, Shen Ying, Shen Qunshan, Zhang Wen, Wang Jiaxiong, Tang Shuyan, Wu Huan, Tian Shixiong, Cong Jiangshan, He Xiaojin, Jin Li, Zhang Feng, Jiang Xiaohui, Cao Yunxia

Abstract excerpt

Male infertility is a multifactorial disease with a strong genetic background. Abnormal sperm morphologies have been found to be closely related to male infertility. Here, we conducted whole-exome sequencing in a cohort of 150 Han Chinese men with asthenoteratozoospermia. Two novel hemizygous mutations were identified in USP26, an X-linked gene preferentially expressed in the testis and encoding a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Asthenozoospermia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cysteine Endopeptidases

Share to Heterozygote

Share to Models, Molecular

Share to Mutation, Missense

Share to Sperm Injections, Intracytoplasmic

Share to Spermatozoa

Source

Open in PubMed Open full text

Identifiers

PMID: 34202084
DOI: 10.3390/cells10071594
PMCID: PMC8307012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Mutations in X-Linked, USP26-Induced Asthenoteratozoospermia and Male Infertility.PMID 34202084Read ↗

Novel mutation in USP26 associated with azoospermia in a Sertoli cell-only syndrome patient.Semantic proximity Read ↗

The association between mutations in ubiquitin-specific protease 26 (USP26) and male infertility: a systematic review and meta-analysis.Semantic proximity Read ↗

Ubiquitin-specific protease (USP26) gene alterations associated with male infertility and recurrent pregnancy loss (RPL) in Iranian infertile patients.Semantic proximity Read ↗

Progress in the genetic studies of spermatogenesis abnormalities.Semantic proximity Read ↗

Novel mutations in ubiquitin-specific protease 26 gene might cause spermatogenesis impairment and male infertility.Semantic proximity Read ↗

A novel frameshift mutation in DNAH6 associated with male infertility and asthenoteratozoospermiaSemantic proximity Read ↗

TENT5D disruption causes oligoasthenoteratozoospermia and male infertility.Semantic proximity Read ↗

Novel mutations in testis-specific ubiquitin protease 26 gene may cause male infertility and hypogonadism.Semantic proximity Read ↗

Association of 370-371insACA, 494T>C, and 1423C>T haplotype in ubiquitin-specific protease 26 gene and male infertility: a meta-analysis.Semantic proximity Read ↗

Unveiling the Genetic Complexity of Teratozoospermia: Integrated Genomic Analysis Reveals Novel Insights into lncRNAs’ Role in Male InfertilitySemantic proximity Read ↗

Splicing Mutation in DNALI1 Causes Male Infertility with Severe Oligoasthenoteratozoospermia in Humans.Semantic proximity Read ↗

Primate-specific SSX1 is required for CPSF6-dependent spermatocyte transcription and human fertilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.