Article
Alterations of the USP26 gene in Caucasian men.
International journal of andrology - 1 Dec 2006
Stouffs Katrien, Lissens Willy, Tournaye Herman, Van Steirteghem André, Liebaers Inge
Abstract excerpt
The Ubiquitin Specific Protease 26 gene is a testis-specific gene that is located on the X chromosome. Sequence variants of this gene were previously reported in men with azoospermia caused by defects at the level of spermatogenesis. Especially a cluster of three changes (c.370_371insACA, c.494T>C and c.1423C>T) was frequently observed. To further define the role of this cluster of sequence variants in the USP26...
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