Article
Of mice and malaria mutants: unravelling the genetics of drug resistance using rodent malaria models.
Trends in parasitology - 1 May 2001
Carlton J M, Hayton K, Cravo P V, Walliker D
Abstract excerpt
It is well recognized that drug resistance is the most significant obstacle to gaining effective malaria control. Despite the enormous advances in the knowledge of the biochemistry and molecular biology of malaria parasites, only a few genes determining resistance to the commonly used drugs have been identified. The idea that rodent malaria parasites should be exploited more widely for such work, in view of the...
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