Article
A decreased level of FtsZ is responsible for inviability of RNase E-deficient cells.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2005
Takada Ayako, Nagai Kazuo, Wachi Masaaki
Abstract excerpt
The endoribonuclease RNase E, encoded by the essential gene rne, plays a major role in cellular RNA metabolism, i.e. maturation of functional RNAs such as rRNA and tRNA, degradation of many mRNAs and processing of the ftsZ mRNA which encodes the essential cell division protein FtsZ. RNase E function is somehow regulated by the RNA binding protein Hfq. We found that temperature-sensitive colony formation of a...
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