Article
[The Jo-1 Syndrome--immunological findings and clinical manifestations].
Medizinische Klinik (Munich, Germany : 1983) - 15 Mar 2005
Seiberlich Bettina, Hunzelmann Nicolas, Roers Axel, Weber Manfred, Schulze-Lohoff Eckhard
Abstract excerpt
El The Jo-1 syndrome is an autoimmune disease which is characterized by the presence of autoantibodies against the Jo-1 antigen. The designation Jo-1 is derived from the name of the first patient (John P.) who was tested positive for this antibody. This patient suffered from polymyositis and fibrosing alveolitis. The Jo-1 antigen was identified as histidyl-transfer-RNA synthetase present in the cytosol. The Jo-1...
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