Characterization of a very virulent Marek's disease virus mutant expressing the pp38 protein from the serotype 1 vaccine strain CVI988/Rispens.

doi:10.1007/s11262-005-2202-2

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Article

Characterization of a very virulent Marek's disease virus mutant expressing the pp38 protein from the serotype 1 vaccine strain CVI988/Rispens.

Virus genes - 1 Aug 2005

Lee Lucy F, Cui Xiaoping, Cui Zhizhong, Gimeno Isabel, Lupiani Blanca, Reddy Sanjay M

Abstract excerpt

Marek's disease virus (MDV), a highly cell-associated oncogenic chicken herpesvirus, causes Marek's disease in domestic chickens. A unique phosphoprotein of MDV, pp38, has previously been associated with the maintenance of transformation in MDV-induced tumor cell lines. However, recently, the biological properties of a deletion mutant virus (rMd5Deltapp38) revealed that pp38 is involved in early cytolytic...

Topics

Amino Acid Sequence
Animals
Antibodies, Viral
Antigens, Viral
Chickens
Female
Gene Expression
Herpesvirus 2, Gallid
Male
Marek Disease
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phosphoproteins

Poultry Diseases

Sequence Alignment

Viral Vaccines

Virulence

Source

Open in PubMed

Identifiers

PMID: 15965611
DOI: 10.1007/s11262-005-2202-2

Provenance

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Characterization of a very virulent Marek's disease virus mutant expressing the pp38 protein from the serotype 1 vaccine strain CVI988/Rispens.PMID 15965611Read ↗

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