Article
Detection of hepatitis C virus (HCV) in serum and peripheral-blood mononuclear cells from HCV-monoinfected and HIV/HCV-coinfected persons.
The Journal of infectious diseases - 15 Jul 2005
Blackard Jason T, Smeaton Laura, Hiasa Yoichi, Horiike Norio, Onji Morikazu, Jamieson Denise J, Rodriguez Irma, Mayer Kenneth H, Chung Raymond T
Abstract excerpt
It has been speculated that hepatitis C virus (HCV) replicates in peripheral-blood mononuclear cells (PBMCs), which, therefore, may be a site for interaction with human immunodeficiency virus (HIV). We used strand-specific real-time polymerase chain reaction to detect HCV RNA in 28 HCV-monoinfected and 20 HIV/HCV-coinfected women. At the first visit, positive-strand HCV RNA was detected in serum samples from 89%...
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