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Article

Carcinogenic Potential of Ovulatory Genotoxicity1

16 Jun 2005

Abstract excerpt

Ovulation is a rate-limiting event for the perpetuation of a species; unfortunately, it imparts a cancer risk. Reactive oxidants generated during the mechanics of ovulatory follicular rupture damage the DNA of ovarian surface epithelial cells that are located within a limited diffusion radius. Those cells that survive the trauma of ovulation, along the margins of a ruptured follicle, proliferate and migrate to...

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Share to Ovarian cancer diagnosis and treatment
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PMID: 15958727
DOI: 10.1095/biolreprod.105.042622

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