Article
Increase in genetic diversity of Haemophilus influenzae serotype b (Hib) strains after introduction of Hib vaccination in The Netherlands.
Journal of clinical microbiology - 1 Jun 2005
Schouls Leo M, van der Ende Arie, van de Pol Ingrid, Schot Corrie, Spanjaard Lodewijk, Vauterin Paul, Wilderbeek Dorus, Witteveen Sandra
Abstract excerpt
Recently, there has been an increase in The Netherlands in the number of cases of invasive disease caused by Haemophilus influenzae serotype b (Hib). To study a possible change in the Hib population that could explain the rise in incidence, a multiple-locus variable number tandem repeats analysis (MLVA) was developed to genotype H. influenzae isolates. The MLVA enabled the differentiation of H. influenzae...
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