Article
Development of a PCR-based assay for detection, quantification, and genotyping of human adenoviruses.
Clinical chemistry - 1 Aug 2005
Chmielewicz Barbara, Nitsche Andreas, Schweiger Brunhilde, Ellerbrok Heinz
Abstract excerpt
BACKGROUND: Adenoviruses (AdVs) can cause serious disease in immunosuppressed patients, particularly those undergoing allogeneic stem cell transplantation. A method for virus quantification in clinical specimens is essential for monitoring patient adenoviral loads and evaluating new therapeutic approaches. METHODS: We developed a PCR-based assay that combines detection and genotyping of human AdVs, targeting a...
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