Article
Expression of VEGF and its receptors in different brain tumors.
Neurological research - 1 Jun 2005
Huang Hongguang, Held-Feindt Janka, Buhl Ralf, Mehdorn Hubertus M, Mentlein Rolf
Abstract excerpt
INTRODUCTION: Vascular endothelial growth factor (VEGF) and its receptors VEGFR-1 and -2 are considered to play a major in tumor angiogenesis, which is a prerequisite for growth of solid tumors. Glioblastoma multiforme is a prominent example of VEGF-induced tumor vascularization; however, little is known about VEGF and in particular VEGFR expression in other types of brain tumors. METHODS: VEGFR mRNA was...
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