Article
Enhanced protein kinase B/Akt signalling in pituitary tumours.
Endocrine-related cancer - 1 Jun 2005
Musat M, Korbonits M, Kola B, Borboli N, Hanson M R, Nanzer A M, Grigson J, Jordan S, Morris D G, Gueorguiev M, Coculescu M, Basu S, Grossman A B
Abstract excerpt
Pituitary tumours have previously been shown to harbour several abnormalities that cause deregulation of the cell cycle, particularly down-regulation of expression of the cyclin-dependent kinase inhibitor p27. However, it has been unclear whether these are the primary initiating events, or are se...
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