Article
Genetic linkage of nevirapine resistance mutations in HIV type 1 seven days after single-dose nevirapine.
AIDS research and human retroviruses - 1 Apr 2005
Jones Dana, Parkin Neil, Hudelson Sarah E, Guay Laura A, Musoke Philippa, Mmiro Francis, Jackson J Brooks, Eshleman Susan H
Abstract excerpt
The HIVNET 012 trial in Uganda demonstrated that a regimen of single-dose nevirapine (NVP) can prevent HIV-1 mother-to-child transmission. Previous studies show that HIV-1 with one or more NVP resistance (NVPR) mutations can be selected in many women as early as 7 days after single-dose NVP. We evaluated the genetic linkage of NVPR mutations in plasma from women in HIVNET 012 collected 7 days after single-dose...
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