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Article

Lys418Asn polymorphism of the alpha2-adrenoceptor gene relates to serum uric acid levels but not to insulin sensitivity.

Hypertension (Dallas, Tex. : 1979) - 1 Jul 2005

Masuo Kazuko, Katsuya Tomohiro, Fu Yuxiao, Rakugi Hiromi, Ogihara Toshio, Tuck Michael L

Abstract excerpt

Hyperuricemia is associated with cardiovascular risk. The present study examines the association between serum uric acid (UA) elevation and the alpha2-, beta2-, and beta3-adrenoceptor polymorphisms. In 219 nonobese, normotensive, normouricemic (serum UA <6.5 mg/dL at entry) men, serum UA, plasma norepinephrine (NE), the homeostasis model assessment of insulin resistance (HOMA-IR), body mass index, total body fat...

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Identifiers

PMID: 15939803
DOI: 10.1161/01.HYP.0000170464.41776.98

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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