Transcriptional regulation of the flavohemoglobin gene for aerobic nitric oxide detoxification by the second nitric oxide-responsive regulator of Pseudomonas aeruginosa.

doi:10.1128/JB.187.12.3960-3968.2005

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Article

Transcriptional regulation of the flavohemoglobin gene for aerobic nitric oxide detoxification by the second nitric oxide-responsive regulator of Pseudomonas aeruginosa.

Journal of bacteriology - 1 Jun 2005

Arai Hiroyuki, Hayashi Michiko, Kuroi Azusa, Ishii Masaharu, Igarashi Yasuo

Abstract excerpt

The regulatory gene for a sigma54-dependent-type transcriptional regulator, fhpR, is located upstream of the fhp gene for flavohemoglobin in Pseudomonas aeruginosa. Transcription of fhp was induced by nitrate, nitrite, nitric oxide (NO), and NO-generating reagents. Analysis of the fhp promoter activity in mutant strains deficient in the denitrification enzymes indicated that the promoter was regulated by NO or...

Topics

Aerobiosis
Bacterial Proteins
DNA-Binding Proteins
DNA-Directed RNA Polymerases
Gene Expression Regulation, Bacterial
Genes, Regulator
Hemeproteins
Mutation
Nitric Oxide
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pseudomonas aeruginosa

RNA Polymerase Sigma 54

Sigma Factor

Time Factors

Transcription Factors

Transcription, Genetic

Up-Regulation

Source

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Identifiers

PMID: 15937158
DOI: 10.1128/JB.187.12.3960-3968.2005
PMCID: PMC1151720

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