Article
Regulation of Pseudomonas aeruginosa hemF and hemN by the dual action of the redox response regulators Anr and Dnr.
Molecular microbiology - 1 Aug 1998
Rompf A, Hungerer C, Hoffmann T, Lindenmeyer M, Römling U, Gross U, Doss M O, Arai H, Igarashi Y, Jahn D
Abstract excerpt
The oxidative decarboxylation of coproporphyrinogen III catalysed by an oxygen-dependent oxidase (HemF) and an oxygen-independent dehydrogenase (HemN) is one of the key regulatory points of haem biosynthesis in Pseudomonas aeruginosa. To investigate the oxygen-dependent regulation of hemF and hemN, the corresponding genes were cloned from the P. aeruginosa chromosome. Recognition sequences for the Fnr-type...
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