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Article

Maternal HLA Ib Polymorphisms in Pregnancy Allo-Immunization.

Frontiers in immunology - 1 Jan 2021

Persson Gry, Picard Christophe, Marin Gregory, Isgaard Cecilie, Stæhr Christina Seefeldt, Molinari Nicolas, Chiaroni Jacques, Lebech Morten, Hviid Thomas Vauvert F, Di Cristofaro Julie

Abstract excerpt

During pregnancy the formation of alloreactive anti-human leukocyte antigen (HLA) antibodies are a major cause of acute rejection in organ transplantation and of adverse effects in blood transfusion. The purpose of the study was to identify maternal HLA class Ib genetic factors associated with anti-HLA allo-immunization in pregnancy and the degree of tolerance estimated by IgG4 expression. In total, 86...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33859649
DOI: 10.3389/fimmu.2021.657217
PMCID: PMC8042285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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