Article
Is the Val16Ala manganese superoxide dismutase polymorphism associated with the aging process?
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Apr 2005
Taufer Maristela, Peres Alessandra, de Andrade Vanessa Moraes, de Oliveira Graziela, Sá Gustavo, do Canto Margo Etiene Pazzato, dos Santos Adriana Ritter, Bauer Moisés E, da Cruz Ivana Beatrice Mânica
Abstract excerpt
Oxidative stress has been related to aging. Recent evidences suggest that a genetic dimorphism that encodes for either alanine or valine in superoxide dismutase (SOD2) is involved with oxidative stress. However, the current literature is still controversial, and the potential role of the Ala16Val polymorphism in human aging needs to be established. Here we investigated the role of the SOD2 polymorphism in: a)...
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