Article
Bone mineral density in men with genetic hemochromatosis and HFE gene mutation.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Dec 2005
Guggenbuhl P, Deugnier Y, Boisdet J F, Rolland Y, Perdriger A, Pawlotsky Y, Chalès G
Abstract excerpt
Genetic hemochromatosis (GH) is an iron overload disorder mainly due to the C282Y mutation of the HFE gene. The possibility of bone involvement was only recently recognized. The aims of this study were to assess bone mineral density (BMD) and bone remodeling in men with GH, and to examine the influence of iron overload. Thirty-eight men (mean age 47.2+/-9.4 years) with well-defined HFE-related GH were studied....
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