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Article

Treatment with IFN-gamma increases serum levels of Th1 chemokines and decreases those of Th2 chemokines in patients with mycosis fungoides.

Journal of dermatological science - 1 Jun 2005

Hino Ryosuke, Shimauchi Takatoshi, Tokura Yoshiki

Abstract excerpt

BACKGROUND: Interferon-gamma (IFN-gamma) is used for the treatment of mycosis fungoides, which is a Th2 neoplasm with elevation of serum Th2 chemokines. Although therapeutic effectiveness of IFN-gamma is caused at least partly by augmented activity of cytotoxic T cells against the tumor cells, its modulation on chemokine production remains unknown. OBJECTIVE: Alterations in the serum levels of Th1 chemokines,...

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Identifiers

PMID: 15927812
DOI: 10.1016/j.jdermsci.2005.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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