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Article

A genetic analysis of deltex and its interaction with the Notch locus in Drosophila melanogaster.

Genetics - 1 May 1992

Gorman M J, Girton J R

Abstract excerpt

During Drosophila development networks of genes control the developmental pathways that specify cell fates. The Notch gene is a well characterized member of some cell fate pathways, and several other genes belonging to these same pathways have been identified because they share a neurogenic null phenotype with Notch. However, it is unlikely that the neurogenic genes represent all of the genes in these pathways....

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Drosophila melanogaster
Extremities
Eye
Female
Genetic Complementation Test
Male
Mutation
Phenotype
Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Wings, Animal

Source

Open in PubMed Open full text

Identifiers

PMID: 1592246
DOI: 10.1093/genetics/131.1.99
PMCID: PMC1204970

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1592246-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A genetic analysis of deltex and its interaction with the Notch locus in Drosophila melanogaster.PMID 1592246Read ↗

deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster.Semantic proximity Read ↗

Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling.Semantic proximity Read ↗

The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase.Semantic proximity Read ↗

The first deltex null mutant indicates tissue-specific deltex-dependent Notch signaling in Drosophila.Semantic proximity Read ↗

Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway.Semantic proximity Read ↗

A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein.Semantic proximity Read ↗

The First Defined Null Allele of the Notch Regulator, a Suppressor of Deltex: Uncovering Its Novel Roles in Drosophila melanogaster Oogenesis.Semantic proximity Read ↗

Genetic regions that interact with loss- and gain-of-function phenotypes of deltex implicate novel genes in Drosophila Notch signaling.Semantic proximity Read ↗

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.Semantic proximity Read ↗

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.Semantic proximity Read ↗

Down-regulation of Notch target gene expression by Suppressor of deltex.Semantic proximity Read ↗

A functional analysis of Notch mutations in Drosophila.Semantic proximity Read ↗

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