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Article

Complement Protein Isoforms in CSF as Possible Biomarkers for Neurodegenerative Disease

1 Jan 2005

Abstract excerpt

It has been suggested that the activation of the complement system is involved in the pathogenesis of several neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS). Here, the CSF expression levels of complement proteins C3b, C4b, factor B, and factor H were compared between normal subjects and patients diagnosed with AD, PD, MS, and neurosyphilis. The...

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PMID: 15920296
DOI: 10.1155/2005/806573

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