In Vivo and In Vitro Expression of Connexins in the Human Corneal Epithelium

Abstract excerpt

PURPOSE: This study is designed to provide a comprehensive expression profile of connexins in the human corneal epithelium (in vivo) and in cultured primary corneal epithelial cells (PCECs) (in vitro). It also evaluates the pathologic effects of a pathogenic missense mutation in Cx26, which causes keratitis-ichthyosis-deafness syndrome (KIDS), a rare genetic disorder with corneal involvement. METHODS: RT-PCR...

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