Article
Single-locus control of saccharin intake in BXD/Ty recombinant inbred (RI) mice: some methodological implications for RI strain analysis.
Behavior genetics - 1 Jan 1992
Belknap J K, Crabbe J C, Plomin R, McClearn G E, Sampson K E, O'Toole L A, Gora-Maslak G
Abstract excerpt
The sac locus, with a major effect on saccharin preference, was discovered by Fuller (1974) in C57BL/6J (B6), DBA/2J (D2), and derived crosses, and is now supported in the BXD/Ty recombinant inbred (RI) series by a marked bimodal distribution in saccharin preference among 20 strains. The B6 allele led to increased saccharin preference compared to the D2 allele. Since the search for bimodal distributions...
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