Article
The instability of the neural crest phenotypes: Schwann cells can differentiate into myofibroblasts.
The International journal of developmental biology - 1 Jan 2005
Real Carla, Glavieux-Pardanaud Corinne, Vaigot Pierre, Le-Douarin Nicole, Dupin Elisabeth
Abstract excerpt
In the vertebrate embryo, the neural crest cells (NCCs) that migrate out from the neural primordium yield multiple phenotypes, including melanocytes, peripheral neurones and glia and, in the head, cartilage, bone, connective cells and myofibroblasts / vascular smooth muscle cells (SMCs). The differentiation of pluripotent NCCs is mainly directed by local growth factors. Even at postmigratory stages, NC-derived...
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