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Toll‐like Receptor 2‐Mediated Gene Expression in Epithelial Cells During <i>Helicobacter pylori</i> Infection

16 May 2005

Abstract excerpt

BACKGROUND: Helicobacter pylori is the major pathogen causing chronic gastritis and peptic ulcer disease and is closely linked to gastric malignancy. We have previously shown that H. pylori-induced NF-(kappa)B activation and interleukin (IL)-8 secretion are mediated by Toll-like receptor (TLR) 2 in epithelial cells. However, the TLR2-mediated global gene expression profile of the epithelial cell during H. pylori...

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PMID: 15904477
DOI: 10.1111/j.1523-5378.2005.00311.x

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