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Article

Identification of a dysfunctional missense single nucleotide variant of human adenylyl cyclase VI.

Clinical pharmacology and therapeutics - 1 Apr 2005

Gros Robert, Ding Qingming, Cao Henian, Main Tony, Hegele Robert A, Feldman Ross D

Abstract excerpt

Genetic variants have been described for a range of G protein-coupled receptors (as well as for G proteins) linked to adenylyl cyclase. Furthermore, expression of these variants resulted in alterations in receptor-mediated activation of adenylyl cyclase, as well as alterations in more "downstream" effector pathways mediated by cyclic adenosine monophosphate. However, the identification of dysfunctional variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15903125
DOI: 10.1016/j.clpt.2004.11.005

Genes

ADCY6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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