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Article

The relationship between C677T methylenetetrahydrofolate reductase gene polymorphism and retinopathy in type 2 diabetes: a meta-analysis.

Journal of human genetics - 1 Jan 2005

Zintzaras Elias, Chatzoulis Dimitrios Z, Karabatsas Costas H, Stefanidis Ioannis

Abstract excerpt

The association between retinopathy in type 2 diabetes [diabetic retinopathy (DR)] and the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene has been investigated in several case-control studies. These studies rendered contradictory results, some indicating that the polymorphism is associated with the risk of developing DR whereas others concluded there is no association. To shed light on...

Read the complete abstract on PubMed

Topics

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Share to Diabetes Mellitus, Type 2
Share to Diabetic Retinopathy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MTHFR gene

Share to Genetic Predisposition to Disease

Share to Genetics, Population

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Odds Ratio

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 15902512
DOI: 10.1007/s10038-005-0250-z

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The relationship between C677T methylenetetrahydrofolate reductase gene polymorphism and retinopathy in type 2 diabetes: a meta-analysis.PMID 15902512Read ↗

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