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Article

Frequent genomic abnormalities at TWIST in human pediatric osteosarcomas.

International journal of cancer - 10 Nov 2005

Entz-Werlé Natacha, Stoetzel Corinne, Berard-Marec Perrine, Kalifa Chantal, Brugiere Laurence, Pacquement Hélène, Schmitt Claudine, Tabone Marie-Dominique, Gentet Jean-Claude, Quillet Robert, Oudet Pierre, Lutz Patrick, Babin-Boilletot Annie, Gaub Marie-Pierre, Perrin-Schmitt Fabienne

Abstract excerpt

The identification of genes as markers for chromosome aberrations in specific tumors might facilitate oncogenesis mechanism comprehension, cancer detection, prediction of clinical outcomes, and response to therapy. Previous physiologic and oncologic data identified the TWIST gene as a marker for mesodermal derivative and bone tissue differentiation, but its contribution to bone malignancies has not been...

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Identifiers

PMID: 15900593
DOI: 10.1002/ijc.21068

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent genomic abnormalities at TWIST in human pediatric osteosarcomas.PMID 15900593Read ↗

Involvement of MET/TWIST/APC Combination or the Potential Role of Ossification Factors in Pediatric High-Grade Osteosarcoma OncogenesisSemantic proximity Read ↗

A twist tale of cancer metastasis and tumor angiogenesis.Semantic proximity Read ↗

TWIST1 expression is associated with high-risk neuroblastoma and promotes primary and metastatic tumor growthSemantic proximity Read ↗

Opposite patterns of association of <i>TWIST1</i> expression with patient survival in SHH and Group 4 medulloblastomaSemantic proximity Read ↗

Twist‐ing cell fate: Mechanistic insights into the role of twist in lineage specification/differentiation and tumorigenesisSemantic proximity Read ↗

Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt ActivationSemantic proximity Read ↗

A tale with a Twist: a developmental gene with potential relevance for metabolic dysfunction and inflammation in adipose tissueSemantic proximity Read ↗

Association of germline or somatic TP53 missense mutation with oncogene amplification in tumors developed in patients with Li-Fraumeni or Li-Fraumeni-like syndrome.Semantic proximity Read ↗

A de novo balanced translocation t(7;12)(p21.2;p12.3) in a patient with Saethre-Chotzen-like phenotype downregulates TWIST and an osteoclastic protein-tyrosine phosphatase, PTP-oc.Semantic proximity Read ↗

Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome.Semantic proximity Read ↗

Targeted Apc;Twist Double-Mutant Mice: A New Model of Spontaneous Osteosarcoma That Mimics the Human DiseaseSemantic proximity Read ↗

Mutations of the TWIST gene in the Saethre-Chotzen syndrome.Semantic proximity Read ↗

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