Article
Tolerance induction by bone marrow transplantation in a multiple sclerosis model.
Blood - 1 Sept 2005
Herrmann Martin M, Gaertner Susanne, Stadelmann Christine, van den Brandt Jens, Böscke Robert, Budach Wilfried, Reichardt Holger M, Weissert Robert
Abstract excerpt
Experimental autoimmune encephalomyelitis (EAE) in rats is a highly valuable model of multiple sclerosis (MS) because it mimics major hallmarks of the human disease. EAE induced with myelin-oligodendrocyte-glycoprotein (MOG) in DA rats is relapsing/remitting, and lesions in the central nervous system show inflammation, demyelination, and axonal and neuronal loss. Recently, bone marrow transplantation (BMT) was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
