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Article

Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.

Molecular and cellular biology - 1 Jun 2005

Reginato Mauricio J, Mills Kenna R, Becker Esther B E, Lynch Danielle K, Bonni Azad, Muthuswamy Senthil K, Brugge Joan S

Abstract excerpt

Epithelial cells organize into cyst-like structures that contain a spherical monolayer of cells that enclose a central lumen. Using a three-dimensional basement membrane culture model in which mammary epithelial cells form hollow, acinus-like structures, we previously demonstrated that lumen form...

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Identifiers

PMID: 15899862
DOI: 10.1128/MCB.25.11.4591-4601.2005
PMCID: PMC1140636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15899862-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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