Article
Variation analysis of the severe acute respiratory syndrome coronavirus putative non-structural protein 2 gene and construction of three-dimensional model.
Chinese medical journal - 5 May 2005
Lu Jia-hai, Zhang Ding-mei, Wang Guo-ling, Guo Zhong-min, Zhang Chuan-hai, Tan Bing-yan, Ouyang Li-ping, Lin Li, Liu Yi-min, Chen Wei-qing, Ling Wen-hua, Yu Xin-bing, Zhong Nan-shan
Abstract excerpt
BACKGROUND: The rapid transmission and high mortality rate made severe acute respiratory syndrome (SARS) a global threat for which no efficacious therapy is available now. Without sufficient knowledge about the SARS coronavirus (SARS-CoV), it is impossible to define the candidate for the anti-SARS targets. The putative non-structural protein 2 (nsp2) (3CL(pro), following the nomenclature by Gao et al, also known...
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