Article
Variability of total serum immunoglobulin E levels from birth to the age of 10 years. A prospective evaluation in a large birth cohort (German Multicenter Allergy Study).
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 2005
Nickel R, Illi S, Lau S, Sommerfeld C, Bergmann R, Kamin W, Forster J, Schuster A, Niggemann B, Wahn U
Abstract excerpt
BACKGROUND: Many environmental factors influence the concentration of total serum IgE (tIgE); however, tIgE synthesis is believed to be under strong genetic influence. Multiple genetic studies on tIgE regulation have been performed. For these population-based studies tIgE was commonly determined at one time-point, assuming that tIgE phenotypes (adjusted for age and gender) are stable over time. OBJECTIVE: We...
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