Article
In silico whole-genome scanning of cancer-associated nonsynonymous SNPs and molecular characterization of a dynein light chain tumour variant.
Oncogene - 8 Sept 2005
Aouacheria Abdel, Navratil Vincent, Wen Wenyu, Jiang Ming, Mouchiroud Dominique, Gautier Christian, Gouy Manolo, Zhang Mingjie
Abstract excerpt
Last decade has led to the accumulation of large amounts of data on cancer genetics, opening an unprecedented access to the mapping of cancer genes in the human genome. Single-nucleotide polymorphisms (SNPs), the most common form of DNA variation in humans, emerge as an invaluable tool for cancer association studies. These genotypic markers can be used to assay how alleles of candidate genes correlate with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.