Article
The mitochondrial ribosome-specific MrpL55 protein is essential in Drosophila and dynamically required during development.
Experimental cell research - 15 Jul 2005
Tselykh Timofey V, Roos Christophe, Heino Tapio I
Abstract excerpt
We report on the essential Drosophila mRpL55 gene conserved exclusively in metazoans. Null mRpL55 mutants did not grow after hatching, moved slowly and died as first instar larvae. MrpL55 is similar to mammalian MRPL55, a protein that, in a large-scale mass spectrometry study, has been found as a mitoribosome-specific large subunit protein. We showed that MrpL55 was localised to the mitochondrion in S2 cells and...
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