Article
Combinatorial expression of phenotypes of different cell lineages in the rat and mouse pituitary.
Annals of the New York Academy of Sciences - 1 Apr 2005
Denef C, Pals K, Hauspie A, Vankelecom H, Seuntjens E
Abstract excerpt
As studied by single cell RT-PCR of pituitary hormones, we demonstrated that the pituitaries of rats and mice contain a subpopulation of cells that express two or more hormone phenotypes typically belonging to lineages that are branched separately early during embryonic development, such as glycoprotein hormone alpha-subunit (alphaGSU) mRNA + PRL mRNA, alphaGSU mRNA + POMC mRNA, and POMC mRNA + GH or PRL mRNA....
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