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Article

Dose- and time-dependent effect of bioactive gel-glass ionic-dissolution products on human fetal osteoblast-specific gene expression.

Journal of biomedical materials research. Part B, Applied biomaterials - 1 Jul 2005

Christodoulou Ioannis, Buttery Lee D K, Saravanapavan Priya, Tai Guangping, Hench Larry L, Polak Julia M

Abstract excerpt

Bioactive glasses dissolve upon immersion in culture medium, and release their constitutive ions into solution. There has been some evidence suggesting that these ionic-dissolution products influence osteoblast-specific processes. Here, the effect of 58S sol-gel-derived bioactive glass (60% SiO(2), 36% CaO, 4% P(2)O(5), in molar percentage) on primary osteoblasts derived from human fetal long bone explant...

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Identifiers

PMID: 15889438
DOI: 10.1002/jbm.b.30249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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