Article
Spleen dendritic cells of recipients of allogeneic but not syngeneic heart grafts internalize donor DNA fragments.
Annals of transplantation - 1 Jan 2004
Interewicz Bozenna, Olszewski Waldemar L, Maksymowicz Michal, Stanislawska Justyna, Szyper Edyta
Abstract excerpt
Microchimerism after allogeneic organ transplantation has been widely documented using DNA identification techniques. However, the question as to whether the detected donor DNA is present in the surviving donor cells, recipient macrophages phagocytizing rejected donor cells or recipient dendritic cells internalizing donor apoptotic bodies or cell fragments has not been answered. We provide evidence that...
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