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Article

Latent KSHV infection of endothelial cells induces integrin beta3 to activate angiogenic phenotypes.

PLoS pathogens - 1 Dec 2011

DiMaio Terri A, Gutierrez Kimberley D, Lagunoff Michael

Abstract excerpt

Kaposi's Sarcoma (KS), the most common tumor of AIDS patients, is a highly vascularized tumor supporting large amounts of angiogenesis. The main cell type of KS tumors is the spindle cell, a cell of endothelial origin, the primary cell type involved in angiogenesis. Kaposi's Sarcoma-associated herpesvirus (KSHV) is the etiologic agent of KS and is likely involved in both tumor formation and the induction of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22174684
DOI: 10.1371/journal.ppat.1002424
PMCID: PMC3234222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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