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Article

Purification and characterization of the vacuolating toxin from Helicobacter pylori.

1 May 1992

Abstract excerpt

A vacuolating toxin was purified to homogeneity from broth culture supernatant of the human gastric bacterium, Helicobacter pylori. The procedure for isolating the toxin included ammonium sulfate precipitation, hydrophobic interactive chromatography, size exclusion chromatography, and anion exchange chromatography, which together resulted in a greater than 5000-fold purification of toxin activity. The molecular...

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PMID: 1587837
DOI: 10.1016/s0021-9258(19)50054-0

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