Article
Effects of plant phenolics and grape extracts from Greek varieties of Vitis vinifera on Mitomycin C and topoisomerase I-induced nicking of DNA.
International journal of molecular medicine - 1 Jun 2005
Stagos Demetrios, Kazantzoglou Georgios, Magiatis Prokopios, Mitaku Sofia, Anagnostopoulos Konstantinos, Kouretas Demetrios
Abstract excerpt
In recent years, a number of reports have shown the anticancer activity of grape extracts and wine against various types of cancer such as breast, lung and gastric cancer. This property is mainly attributed to the plant polyphenols identified in grapes. The aim of the present study was to investigate the mechanisms by which grape extracts and plant polyphenols found in them exert their chemopreventive and...
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