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Article

Evidence for positive selection acting on microcystin synthetase adenylation domains in three cyanobacterial genera.

BMC evolutionary biology - 22 Sept 2008

Tooming-Klunderud Ave, Fewer David P, Rohrlack Thomas, Jokela Jouni, Rouhiainen Leo, Sivonen Kaarina, Kristensen Tom, Jakobsen Kjetill S

Abstract excerpt

BACKGROUND: Cyanobacteria produce a wealth of secondary metabolites, including the group of small cyclic heptapeptide hepatotoxins that constitutes the microcystin family. The enzyme complex that directs the biosynthesis of microcystin is encoded in a single large gene cluster (mcy). mcy genes have a widespread distribution among cyanobacteria and are likely to have an ancient origin. The notable diversity within...

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Identifiers

PMID: 18808704
DOI: 10.1186/1471-2148-8-256
PMCID: PMC2564945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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