Article
The mosaic structure of the mcyABC operon in Microcystis.
Microbiology (Reading, England) - 1 Jul 2008
Tooming-Klunderud Ave, Mikalsen Bjørg, Kristensen Tom, Jakobsen Kjetill S
Abstract excerpt
An extensive study of the mcyABC genes and regions flanking the mcy gene cluster was performed in naturally occurring Microcystis strains. Lack of methylation in strains producing only desmethyl(7)-microcystin was found to be associated with point mutations in substrate-binding sequence motifs of the N-methyltransferase (NMT) domain in McyA. Multiple recombination events giving rise to 'phylogenetic mosaics' were...
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