Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Natural variation in the microcystin synthetase operon mcyABC and impact on microcystin production in Microcystis strains.

Journal of bacteriology - 1 May 2003

Mikalsen Bjørg, Boison Gudrun, Skulberg Olav M, Fastner Jutta, Davies William, Gabrielsen Tove M, Rudi Knut, Jakobsen Kjetill S

Abstract excerpt

Toxic Microcystis strains often produce several isoforms of the cyclic hepatotoxin microcystin, and more than 65 isoforms are known. This has been attributed to relaxed substrate specificity of the adenylation domain. Our results show that in addition to this, variability is also caused by geneti...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Transfer, Horizontal
Share to Microcystins
Share to Microcystis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multigene Family

Share to Operon

Share to Peptide Synthases

Share to Peptides, Cyclic

Share to Sequence Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 12700256
DOI: 10.1128/JB.185.9.2774-2785.2003
PMCID: PMC154389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12700256-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Natural variation in the microcystin synthetase operon mcyABC and impact on microcystin production in Microcystis strains.PMID 12700256Read ↗

The mosaic structure of the mcyABC operon in Microcystis.Semantic proximity Read ↗

Congruence between mcy based genetic type and microcystin composition within the populations of toxic Microcystis in a Plateau Lake, China.Semantic proximity Read ↗

Evidence for positive selection acting on microcystin synthetase adenylation domains in three cyanobacterial genera.Semantic proximity Read ↗

Convergent evolution of [D-Leucine1] microcystin-LR in taxonomically disparate cyanobacteriaSemantic proximity Read ↗

Diversity of microcystin-producing genotypes in Brazilian strains of Microcystis (Cyanobacteria).Semantic proximity Read ↗

Recombination, cryptic clades and neutral molecular divergence of the microcystin synthetase (mcy) genes of toxic cyanobacterium Microcystis aeruginosa.Semantic proximity Read ↗

Genetic identification of microcystin ecotypes in toxic cyanobacteria of the genus Planktothrix.Semantic proximity Read ↗

Metagenomic and Metatranscriptomic Insights into Population Diversity of Microcystis Blooms: Spatial and Temporal Dynamics of mcy Genotypes, Including a Partial Operon That Can Be Abundant and Expressed.Semantic proximity Read ↗

Evidence for recombination in the microcystin synthetase (mcy) genes of toxic cyanobacteria Microcystis spp.Semantic proximity Read ↗

Diversity of microcystin genes within a population of the toxic cyanobacterium Microcystis spp. in Lake Wannsee (Berlin, Germany).Semantic proximity Read ↗

Integrating phylogeny, geographic niche partitioning and secondary metabolite synthesis in bloom-forming Planktothrix.Semantic proximity Read ↗

Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-polyketide synthetase system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.