Article
A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity.
Blood - 1 Sept 2005
Kotton Darrell N, Fabian Attila J, Mulligan Richard C
Abstract excerpt
A number of recent reports have documented that cells possessing hematopoietic-reconstitution ability can be identified and isolated from a variety of solid organs in the adult animal. In all studies to date, however, purified organ-derived stem cells demonstrate a diminished repopulating capacity relative to that of purified bone marrow-derived hematopoietic stem cells (BM HSCs). It has therefore been unclear...
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