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Article

Activation of extrathymic T cells in the liver and reciprocal inactivation of intrathymic T cells by bacterial stimulation.

Cellular immunology - 1 Jun 1992

Abo T, Kusumi A, Seki S, Ohteki T, Sugiura K, Masuda T, Rikiishi H, Iiai T, Kumagai K

Abstract excerpt

We recently demonstrated that the liver might be a major site of extrathymic T cell differentiation, including both alpha beta and gamma delta T cells. This extrathymic pathway in the liver, which has a relatively minor role in normal young mice, is activated in mice under bacterial stimulation. In the present study, we investigated how the extrathymic and intrathymic T cell differentiations were mutually related...

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Identifiers

PMID: 1586952
DOI: 10.1016/0008-8749(92)90274-s

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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