Article
Molecular genetics of multiple endocrine neoplasia types 1 and 2.
Nature reviews. Cancer - 1 May 2005
Marx Stephen J
Abstract excerpt
Six multiple endocrine neoplasia (MEN) syndromes have received a level of attention that might seem disproportionate to their low prevalence. The attention has been given because their hormonal excesses cause striking metabolic expressions and because they might clarify pathways disrupted in more common tumours. The recent discovery of the main gene in each MEN syndrome has furthered our understanding of not only...
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