Article
Genotype and plasma concentration of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2005
Loew Michael, Hoffmann Michael M, Koenig Wolfgang, Brenner Hermann, Rothenbacher Dietrich
Abstract excerpt
OBJECTIVE: Cysteine proteases and their inhibitors such as cystatin C are assumed to play an important role in the pathogenesis of atherosclerosis and coronary heart disease (CHD). The aim of the study was to investigate the impact of cystatin C polymorphisms on cystatin C plasma levels and on prognosis of patients with CHD. METHODS AND RESULTS: Four polymorphisms in the promoter and exon 1 of the cystatin C gene...
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